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Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion
While the build-up of oxidized proteins within cells is believed to be toxic, there is currently no evidence linking protein carbonylation and cell death. In the present study, we show that incubation of nPC12 (neuron-like PC12) cells with 50 μM DEM (diethyl maleate) leads to a partial and transient...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Neurochemistry
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322383/ https://ncbi.nlm.nih.gov/pubmed/22376187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110064 |
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