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Gene fragmentation in bacterial draft genomes: extent, consequences and mitigation

BACKGROUND: Ongoing technological advances in genome sequencing are allowing bacterial genomes to be sequenced at ever-lower cost. However, nearly all of these new techniques concomitantly decrease genome quality, primarily due to the inability of their relatively short read lengths to bridge certai...

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Sonraí Bibleagrafaíochta
Main Authors: Klassen, Jonathan L, Currie, Cameron R
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322347/
https://ncbi.nlm.nih.gov/pubmed/22233127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-14
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