Autophagy Links Inflammasomes to Atherosclerotic Progression

We investigated the role of autophagy in atherosclerosis. During plaque formation in mice, autophagic markers co-localized predominantly with macrophages (mϕ). Atherosclerotic aortas had elevated levels of p62, suggesting that dysfunctional autophagy is characteristic of plaques. To determine if aut...

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Bibliografiske detaljer
Main Authors: Razani, Babak, Feng, Chu, Coleman, Trey, Emanuel, Roy, Wen, Haitao, Hwang, Seungmin, Ting, Jenny P., Virgin, Herbert W., Kastan, Michael B., Semenkovich, Clay F.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322320/
https://ncbi.nlm.nih.gov/pubmed/22440612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.02.011
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