A Non-peptide Angiotensin II Type 2 Receptor Agonist Does Not Attenuate Post-Myocardial Infarction Left Ventricular Remodeling in Mice

Cardiac overexpression of the angiotensin II type 2 receptor (AT(2)R) attenuates left ventricular (LV) remodeling after myocardial infarction (MI) in transgenic mice. We hypothesized that a novel nonpeptide AT(2)R agonist, Compound 21 (C21), would attenuate post-MI LV remodeling. Fifty nine mice wer...

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Detalhes bibliográficos
Main Authors: Jehle, Alexander B., Xu, Yaqin, DiMaria, Joseph M., French, Brent A., Epstein, Frederick H., Berr, Stuart S., Roy, Rene J., Kemp, Brandon A., Carey, Robert M., Kramer, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322306/
https://ncbi.nlm.nih.gov/pubmed/22157261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3182444110
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