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Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins.

The 'octamer' sequence, ATGCAAAT or its complement ATTTGCAT, is a key element for the transcriptional regulation of immunoglobulin genes in B-lymphocytes as well as a number of housekeeping genes in all cell types. In lymphocytes, the octamer-binding protein Oct-2A and variants thereof are...

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Autori principali: Schreiber, E, Harshman, K, Kemler, I, Malipiero, U, Schaffner, W, Fontana, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC332229/
https://ncbi.nlm.nih.gov/pubmed/2216722
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