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Knockdown of the sphingosine-1-phosphate receptor S1PR1 reduces pain behaviors induced by local inflammation of the rat sensory ganglion

Sphingosine 1-phosphate (S1P) is a key immune mediator regulating migration of immune cells to sites of inflammation. S1P actions are mediated by a family of five G protein-coupled receptors. Sensory neurons express many of these receptors, and in vitro S1P has excitatory effects on small-diameter s...

詳細記述

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書誌詳細
主要な著者: Xie, Wenrui, Strong, Judith A., Kays, Joanne, Nicol, Grant D., Zhang, Jun-Ming
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322267/
https://ncbi.nlm.nih.gov/pubmed/22445889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.03.019
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