Deferoxamine reverses radiation induced hypovascularity during bone regeneration & repair in the murine mandible

BACKGROUND: Deferoxamine (DFO) is an iron-chelating agent that has also been shown to increase angiogenesis. We hypothesize that the angiogenic properties of DFO will improve bone regeneration in distraction osteogenesis (DO) after x-ray radiation therapy (XRT) by restoring the vascularity around th...

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Hlavní autoři: Farberg, Aaron S., Jing, Xi L., Monson, Laura A., Donneys, Alexis, Tchanque-Fossuo, Catherine N., Deshpande, Sagar S., Buchman, Steven R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322244/
https://ncbi.nlm.nih.gov/pubmed/22314387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2012.01.019
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