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Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics
We present a predictive bioprocess design strategy employing cell- and molecular-level analysis of rate-limiting steps in human pluripotent stem cell (hPSC) expansion and differentiation, and apply it to produce definitive endoderm (DE) progenitors using a scalable directed-differentiation technolog...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321926/ https://ncbi.nlm.nih.gov/pubmed/22139975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24375 |
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