Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells

Surprisingly little is known about the interaction of human blood mononuclear cells with viruses. Here, we show that monocytes are the predominant cell type infected when peripheral blood mononuclear cells are exposed to viruses ex vivo. Remarkably, infection with vesicular stomatitis virus, vaccini...

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Bibliographic Details
Main Authors: Hou, Wanqiu, Gibbs, James S., Lu, Xiuju, Brooke, Christopher B., Roy, Devika, Modlin, Robert L., Bennink, Jack R., Yewdell, Jonathan W.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321872/
https://ncbi.nlm.nih.gov/pubmed/22310910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-379479
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