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Effective connectivity among brain regions associated with slow temporal summation of C-fiber evoked pain in fibromyalgia patients and healthy controls

Temporal summation of “second pain” (TSSP) or “windup” results from the summation of C-fiber-evoked responses of dorsal-horn neurons. This phenomenon is dependent on stimulus frequency (>0.33 Hz) and relevant to central sensitization and chronic pain. Our previous neuroimaging studies characteriz...

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Detalhes bibliográficos
Main Authors: Craggs, Jason G., Staud, Roland, Robinson, Michael E., Perlstein, William, Price, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321832/
https://ncbi.nlm.nih.gov/pubmed/22480771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2012.01.002
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