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Predicting the clinical efficacy and potential adverse effects of a humanized anticocaine monoclonal antibody
The effects of a humanized monoclonal antibody (mAb) having high affinity and specificity for cocaine in animal models are reviewed. The mAb reduced the concentration of cocaine in the brain of mice after intravenous injection of cocaine. In addition, the mAb increased the concentration of cocaine r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321830/ https://ncbi.nlm.nih.gov/pubmed/22401638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.12.19 |
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