Mutation Pattern of Paired Immunoglobulin Heavy and Light Variable Domains in Chronic Lymphocytic Leukemia B Cells

B-cell chronic lymphocytic leukemia (CLL) patients display leukemic clones bearing either germline or somatically mutated immunoglobulin heavy variable (IGHV ) genes. Most information on CLL immunoglobulins (Igs), such as the definition of stereotyped B-cell receptors (BCRs), was derived from germli...

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Main Authors: Ghiotto, Fabio, Marcatili, Paolo, Tenca, Claudya, Calevo, Maria Grazia, Yan, Xiao-Jie, Albesiano, Emilia, Bagnara, Davide, Colombo, Monica, Cutrona, Giovanna, Chu, Charles C, Morabito, Fortunato, Bruno, Silvia, Ferrarini, Manlio, Tramontano, Anna, Fais, Franco, Chiorazzi, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321824/
https://ncbi.nlm.nih.gov/pubmed/21785810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00104
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