A Dual Role for Diacylglycerol Kinase Generated Phosphatidic Acid in Autoantibody-Induced Neutrophil Exocytosis

Dysregulated release of neutrophil azurophilic granules causes increased tissue damage and amplified inflammation during autoimmune disease. Antineutrophil cytoplasmic antibodies (ANCAs) are implicated in the pathogenesis of small vessel vasculitis and promote adhesion and exocytosis in neutrophils....

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Bibliographic Details
Main Authors: Holden, Neil J, Savage, Caroline O S, Young, Stephen P, Wakelam, Michael J, Harper, Lorraine, Williams, Julie M
Format: Artigo
Language:Inglês
Published: ScholarOne 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321818/
https://ncbi.nlm.nih.gov/pubmed/21833457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00028
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