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A Dual Role for Diacylglycerol Kinase Generated Phosphatidic Acid in Autoantibody-Induced Neutrophil Exocytosis

Dysregulated release of neutrophil azurophilic granules causes increased tissue damage and amplified inflammation during autoimmune disease. Antineutrophil cytoplasmic antibodies (ANCAs) are implicated in the pathogenesis of small vessel vasculitis and promote adhesion and exocytosis in neutrophils....

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Detalhes bibliográficos
Main Authors: Holden, Neil J, Savage, Caroline O S, Young, Stephen P, Wakelam, Michael J, Harper, Lorraine, Williams, Julie M
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321818/
https://ncbi.nlm.nih.gov/pubmed/21833457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00028
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