A Dual Role for Diacylglycerol Kinase Generated Phosphatidic Acid in Autoantibody-Induced Neutrophil Exocytosis

Dysregulated release of neutrophil azurophilic granules causes increased tissue damage and amplified inflammation during autoimmune disease. Antineutrophil cytoplasmic antibodies (ANCAs) are implicated in the pathogenesis of small vessel vasculitis and promote adhesion and exocytosis in neutrophils....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Holden, Neil J, Savage, Caroline O S, Young, Stephen P, Wakelam, Michael J, Harper, Lorraine, Williams, Julie M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: ScholarOne 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321818/
https://ncbi.nlm.nih.gov/pubmed/21833457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00028
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