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Dual Peptide Nucleic Acid- and Peptide-functionalized Shell Crosslinked Nanoparticles Designed to Target mRNA toward the Diagnosis and Treatment of Acute Lung Injury

In this work, multi-functional bio-synthetic hybrid nanostructures were prepared and studied for their potential utility in the recognition and inhibition of mRNA sequences for inducible nitric oxide synthase (iNOS), which are overexpressed at sites of inflammation, such as in cases of acute lung in...

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Detalhes bibliográficos
Main Authors: Shrestha, Ritu, Shen, Yuefei, Pollack, Kevin A., Taylor, John-Stephen A., Wooley, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321742/
https://ncbi.nlm.nih.gov/pubmed/22372643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200629f
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