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Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown()

Histones are highly conserved proteins that organize cellular DNA. These proteins, especially their N-terminal domains, are adorned with many post-translational modifications (PTMs) such as lysine methylation, which are associated with active or repressed transcriptional states. The lysine methyltra...

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Bibliografiske detaljer
Main Authors: Plazas-Mayorca, Mariana D., Bloom, Joshua S., Zeissler, Ulrike, Leroy, Gary, Young, Nicolas L., DiMaggio, Peter A., Krugylak, Leonid, Schneider, Robert, Garcia, Benjamin A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321735/
https://ncbi.nlm.nih.gov/pubmed/20577673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c003307c
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