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Current Alzheimer's disease clinical trials: Methods and placebo outcomes

BACKGROUND: Eighteen-month-long randomized, placebo-controlled clinical trials are common for phase II and phase III drug development for Alzheimer's disease (AD). Yet, no 18-month trial has shown statistically significant outcomes favoring the test drug. We examined characteristics and underly...

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Detalhes bibliográficos
Main Authors: Schneider, Lon S., Sano, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321732/
https://ncbi.nlm.nih.gov/pubmed/19751918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2009.07.038
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