HIV Develops Indirect Cross-resistance to Combinatorial RNAi Targeting Two Distinct and Spatially Distant Sites

Resistance to existing HIV therapies is an increasing problem, and alternative treatments are urgently needed. RNA interference (RNAi), an innate mechanism for sequence-specific gene silencing, can be harnessed therapeutically to treat viral infections, yet viral resistance can still emerge. Here, w...

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Bibliografski detalji
Glavni autori: Shah, Priya S, Pham, Nhung P, Schaffer, David V
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321590/
https://ncbi.nlm.nih.gov/pubmed/22294151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.3
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