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Evolution of domain promiscuity in eukaryotic genomes—a perspective from the inferred ancestral domain architectures()

Most eukaryotic proteins are composed of two or more domains. These assemble in a modular manner to create new proteins usually by the acquisition of one or more domains to an existing protein. Promiscuous domains which are found embedded in a variety of proteins and co-exist with many other domains...

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Detalhes bibliográficos
Main Authors: Cohen-Gihon, Inbar, Fong, Jessica H., Sharan, Roded, Nussinov, Ruth, Przytycka, Teresa M., Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321261/
https://ncbi.nlm.nih.gov/pubmed/21127809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00182a
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