Epigenetic silencing of myogenic gene program by Myb-binding protein 1a suppresses myogenesis

Skeletal myogenesis involves highly coordinated steps that integrate developmental cues at the chromatin of muscle progenitors. Here, we identify Myb-binding protein 1a (Mybbp1a) as a novel negative regulator of muscle-specific gene expression and myoblast differentiation. The mode of action of Mybb...

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Autori principali: Yang, Chang-Ching, Liu, Hsuan, Chen, Shen Liang, Wang, Tzu-Hao, Hsieh, Chia-Ling, Huang, Yi, Chen, Shu-Jen, Chen, Hua-Chien, Yung, Benjamin Yat-Ming, Chin-Ming Tan, Bertrand
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321204/
https://ncbi.nlm.nih.gov/pubmed/22333916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.24
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