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PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression

Maf1 is the ‘master' repressor of RNA polymerase III (Pol III) transcription in yeast, and is conserved in eukaryotes. Maf1 is a phospho-integrator, with unfavourable growth conditions leading to rapid Maf1 dephosphorylation, nuclear accumulation, binding to RNA Pol III at Pol III genes and tra...

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Détails bibliographiques
Auteurs principaux: Oler, Andrew J, Cairns, Bradley R
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321174/
https://ncbi.nlm.nih.gov/pubmed/22333918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.501
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