Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells

BACKGROUND & AIMS: microRNAs (miRs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse not only in the mRNAs they target but in their production; the same hairpin RNA structure can generate mature products from each strand, ter...

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Detalhes bibliográficos
Main Authors: Almeida, Maria I., Nicoloso, Milena S., Zeng, Lizhi, Ivan, Cristina, Spizzo, Riccardo, Gafà, Roberta, Xiao, Lianchun, Zhang, Xinna, Vannini, Ivan, Fanini, Francesca, Fabbri, Muller, Lanza, Giovanni, Reis, Rui M., Zweidler-McKay, Patrick A., Calin, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321100/
https://ncbi.nlm.nih.gov/pubmed/22240480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.12.047
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