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MAP and Kinesin dependent nuclear positioning is required for skeletal muscle function

The basic unit of skeletal muscle in all metazoans is the multinucleate myofiber, within which individual nuclei are regularly positioned(1). The molecular machinery responsible for myonuclear positioning is not known. Improperly positioned nuclei are a hallmark of numerous muscles diseases(2), incl...

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Detalhes bibliográficos
Main Authors: Metzger, Thomas, Gache, Vincent, Xu, Mu, Cadot, Bruno, Folker, Eric S., Richardson, Brian E., Gomes, Edgar R., Baylies, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321085/
https://ncbi.nlm.nih.gov/pubmed/22425998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10914
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