Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

The conversion of chemical energy into mechanical force by AAA+ (ATPases associated with diverse cellular activities) ATPases is integral to cellular processes, including DNA replication, protein unfolding, cargo transport, and membrane fusion(1). The AAA+ ATPase motor cytoplasmic dynein regulates c...

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Hlavní autoři: Firestone, Ari J., Weinger, Joshua S., Maldonado, Maria, Barlan, Kari, Langston, Lance D., O'Donnell, Michael, Gelfand, Vladimir I., Kapoor, Tarun M., Chen, James K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321072/
https://ncbi.nlm.nih.gov/pubmed/22425997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10936
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