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Biological Effect of Lead-212 Localized in the Nucleus of Mammalian Cells: Role of Recoil Energy in the Radiotoxicity of Internal Alpha-Particle Emitters()

The radiochemical dipyrrolidinedithiocarbamato-(212)Pb(II) [(212)Pb(PDC)(2)] is synthesized and its effects on colony formation in cultured Chinese hamster V79 cells are investigated. The cellular uptake, biological retention, subcellular distribution and cytotoxicity of the radiocompound are determ...

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Detalhes bibliográficos
Main Authors: Azure, Michael T., Archer, Ronald D., Sastry, Kandula S. R., Rao, Dandamudi V., Howell, Roger W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321059/
https://ncbi.nlm.nih.gov/pubmed/7938477
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