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Neural Crest Deletion of Dlx3 Leads to Major Dentin Defects through Down-regulation of Dspp

During development, Dlx3 is expressed in ectodermal appendages such as hair and teeth. Thus far, the evidence that Dlx3 plays a crucial role in tooth development comes from reports showing that autosomal dominant mutations in DLX3 result in severe enamel and dentin defects leading to abscesses and i...

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Detalhes bibliográficos
Main Authors: Duverger, Olivier, Zah, Angela, Isaac, Juliane, Sun, Hong-Wei, Bartels, Anne K., Lian, Jane B., Berdal, Ariane, Hwang, Joonsung, Morasso, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320974/
https://ncbi.nlm.nih.gov/pubmed/22351765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326900
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