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Regulated Clearance of Histone Deacetylase 3 Protects Independent Formation of Nuclear Receptor Corepressor Complexes

An important step in transcriptional regulation by corepressors N-CoR and SMRT is the formation of a stable and active histone deacetylase 3 (HDAC3)-containing complex. Although N-CoR and SMRT are thought to bind HDAC3 competitively, multiple studies have shown that they do not interfere with the fu...

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Autors principals: Guo, Chun, Gow, Chien-Hung, Li, Yali, Gardner, Amanda, Khan, Sohaib, Zhang, Jinsong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320956/
https://ncbi.nlm.nih.gov/pubmed/22337871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.327023
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