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Genetic Association Studies of Copy-Number Variation: Should Assignment of Copy Number States Precede Testing?
Recently, structural variation in the genome has been implicated in many complex diseases. Using genomewide single nucleotide polymorphism (SNP) arrays, researchers are able to investigate the impact not only of SNP variation, but also of copy-number variants (CNVs) on the phenotype. The most common...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320903/ https://ncbi.nlm.nih.gov/pubmed/22493684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034262 |
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