Structural and Functional Analysis of the Symmetrical Type I Restriction Endonuclease R.EcoR124I(NT)

Type I restriction-modification (RM) systems are comprised of two multi-subunit enzymes, the methyltransferase (∼160 kDa), responsible for methylation of DNA, and the restriction endonuclease (∼400 kDa), responsible for DNA cleavage. Both enzymes share a number of subunits. An engineered RM system,...

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Bibliographic Details
Main Authors: Taylor, James E., Swiderska, Anna, Artero, Jean-Baptiste, Callow, Philip, Kneale, Geoff
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320862/
https://ncbi.nlm.nih.gov/pubmed/22493743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035263
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