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The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2

During pregnancy, progesterone inhibits the growth-promoting actions of estrogen in the uterus. However, the mechanism for this is not clear. The attenuation of estrogen-mediated proliferation of the uterine epithelium by progesterone is a prerequisite for successful implantation. Our study reveals...

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Hlavní autoři: Li, Quanxi, Kannan, Athilakshmi, DeMayo, Francesco J., Lydon, John P., Cooke, Paul S., Yamagishi, Hiroyuki, Srivastava, Deepak, Bagchi, Milan K., Bagchi, Indrani C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320855/
https://ncbi.nlm.nih.gov/pubmed/21330545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197454
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