Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome

Antiphospholipid (aPL)/anti-β(2) glycoprotein I (anti-β(2)GPI) antibodies stimulates tissue factor (TF) expression within vasculature and in blood cells, thereby leading to increased thrombosis. Several cellular receptors have been proposed to mediate these effects, but no convincing evidence for th...

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Auteurs principaux: Romay-Penabad, Zurina, Aguilar-Valenzuela, Renan, Urbanus, Rolf T., Derksen, Ronald H. W. M., Pennings, Maarten T. T., Papalardo, Elizabeth, Shilagard, Tuya, Vargas, Gracie, Hwang, Yong, de Groot, Philip G., Pierangeli, Silvia S.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Thrombosis and Hemostasis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320849/
https://ncbi.nlm.nih.gov/pubmed/21119114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-299099
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