Statistical Considerations of Optimal Study Design for Human Plasma Proteomics and Biomarker Discovery

[Image: see text] A mass spectrometry-based plasma biomarker discovery workflow was developed to facilitate biomarker discovery. Plasma from either healthy volunteers or patients with pancreatic cancer was 8-plex iTRAQ labeled, fractionated by 2-dimensional reversed phase chromatography and subjecte...

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Main Authors: Zhou, Cong, Simpson, Kathryn L., Lancashire, Lee J., Walker, Michael J., Dawson, Martin J., Unwin, Richard D., Rembielak, Agata, Price, Patricia, West, Catharine, Dive, Caroline, Whetton, Anthony D.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2012
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320746/
https://ncbi.nlm.nih.gov/pubmed/22338609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200636x
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