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Reverse Vaccinology: Developing Vaccines in the Era of Genomics
The sequence of microbial genomes made all potential antigens of each pathogen available for vaccine development. This increased by orders of magnitude potential vaccine targets in bacteria, parasites, and large viruses and revealed virtually all their CD4(+) and CD8(+) T cell epitopes. The genomic...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320742/ https://ncbi.nlm.nih.gov/pubmed/21029963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.017 |
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