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Reverse Vaccinology: Developing Vaccines in the Era of Genomics

The sequence of microbial genomes made all potential antigens of each pathogen available for vaccine development. This increased by orders of magnitude potential vaccine targets in bacteria, parasites, and large viruses and revealed virtually all their CD4(+) and CD8(+) T cell epitopes. The genomic...

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Detalles Bibliográficos
Main Authors: Sette, Alessandro, Rappuoli, Rino
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320742/
https://ncbi.nlm.nih.gov/pubmed/21029963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.017
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