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Reverse Vaccinology: Developing Vaccines in the Era of Genomics

The sequence of microbial genomes made all potential antigens of each pathogen available for vaccine development. This increased by orders of magnitude potential vaccine targets in bacteria, parasites, and large viruses and revealed virtually all their CD4(+) and CD8(+) T cell epitopes. The genomic...

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Bibliografiske detaljer
Main Authors: Sette, Alessandro, Rappuoli, Rino
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320742/
https://ncbi.nlm.nih.gov/pubmed/21029963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.017
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