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Reverse Vaccinology: Developing Vaccines in the Era of Genomics

The sequence of microbial genomes made all potential antigens of each pathogen available for vaccine development. This increased by orders of magnitude potential vaccine targets in bacteria, parasites, and large viruses and revealed virtually all their CD4(+) and CD8(+) T cell epitopes. The genomic...

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Détails bibliographiques
Auteurs principaux: Sette, Alessandro, Rappuoli, Rino
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320742/
https://ncbi.nlm.nih.gov/pubmed/21029963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.017
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