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Reverse Vaccinology: Developing Vaccines in the Era of Genomics

The sequence of microbial genomes made all potential antigens of each pathogen available for vaccine development. This increased by orders of magnitude potential vaccine targets in bacteria, parasites, and large viruses and revealed virtually all their CD4(+) and CD8(+) T cell epitopes. The genomic...

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Bibliografische gegevens
Hoofdauteurs: Sette, Alessandro, Rappuoli, Rino
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320742/
https://ncbi.nlm.nih.gov/pubmed/21029963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.017
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