A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes

Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making it...

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Detalhes bibliográficos
Main Authors: Johnson, Rory, Richter, Nadine, Bogu, Gireesh K., Bhinge, Akshay, Teng, Siaw Wei, Choo, Siew Hua, Andrieux, Lise O., de Benedictis, Cinzia, Jauch, Ralf, Stanton, Lawrence W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320604/
https://ncbi.nlm.nih.gov/pubmed/22496669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002624
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