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Regulation of Mycobacterium tuberculosis-Dependent HIV-1 Transcription Reveals a New Role for NFAT5 in the Toll-Like Receptor Pathway

Tuberculosis (TB) disease in HIV co-infected patients contributes to increased mortality by activating innate and adaptive immune signaling cascades that stimulate HIV-1 replication, leading to an increase in viral load. Here, we demonstrate that silencing of the expression of the transcription fact...

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Bibliografiske detaljer
Main Authors: Ranjbar, Shahin, Jasenosky, Luke D., Chow, Nancy, Goldfeld, Anne E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320587/
https://ncbi.nlm.nih.gov/pubmed/22496647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002620
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