RNA-Seq Mapping and Detection of Gene Fusions with a Suffix Array Algorithm

High-throughput RNA sequencing enables quantification of transcripts (both known and novel), exon/exon junctions and fusions of exons from different genes. Discovery of gene fusions–particularly those expressed with low abundance– is a challenge with short- and medium-length sequencing reads. To add...

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Auteurs principaux: Sakarya, Onur, Breu, Heinz, Radovich, Milan, Chen, Yongzhi, Wang, Yulei N., Barbacioru, Catalin, Utiramerur, Sowmi, Whitley, Penn P., Brockman, Joel P., Vatta, Paolo, Zhang, Zheng, Popescu, Liviu, Muller, Matthew W., Kudlingar, Vidya, Garg, Nriti, Li, Chieh-Yuan, Kong, Benjamin S., Bodeau, John P., Nutter, Robert C., Gu, Jian, Bramlett, Kelli S., Ichikawa, Jeffrey K., Hyland, Fiona C., Siddiqui, Asim S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320572/
https://ncbi.nlm.nih.gov/pubmed/22496636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002464
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