Platelet hyperaggregability in high-fat fed rats: A role for intraplatelet reactive-oxygen species production

BACKGROUND: Adiposity greatly increases the risk of atherothrombotic events, a pathological condition where a chronic state of oxidative stress is reported to play a major role. This study aimed to investigate the involvement of (NO)-soluble guanylyl cyclase (sGC) signaling pathway in the platelet d...

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Detalhes bibliográficos
Main Authors: Monteiro, Priscila F, Morganti, Rafael P, Delbin, Maria A, Calixto, Marina C, Lopes-Pires, Maria E, Marcondes, Sisi, Zanesco, Angelina, Antunes, Edson
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320560/
https://ncbi.nlm.nih.gov/pubmed/22248260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-11-5
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