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Direct Interactions between Calcitonin-Like Receptor (CLR) and CGRP-Receptor Component Protein (RCP) Regulate CGRP Receptor Signaling

Calcitonin gene-related peptide (CGRP) is a neuropeptide with multiple neuroendocrine roles, including vasodilation, migraine, and pain. The receptor for CGRP is a G protein-coupled receptor (GPCR) that requires three proteins for function. CGRP binds to a heterodimer composed of the GPCR calcitonin...

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Hlavní autoři: Egea, Sophie C., Dickerson, Ian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320266/
https://ncbi.nlm.nih.gov/pubmed/22315449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1459
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