N -Ethyl- N -Nitrosourea Induces Retinal Photoreceptor Damage in Adult Rats

Seven-week-old male Lewis rats received a single intraperitoneal injection of N-ethyl-N-nitrosourea (ENU) (100, 200, 400 or 600 mg/kg), and retinal damage was evaluated 7 days after the treatment. Sequential morphological features of the retina and retinal DNA damage, as determined by a TUNEL assay...

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Detalhes bibliográficos
Main Authors: Yoshizawa, Katsuhiko, Sasaki, Tomo, Uehara, Norihisa, Kuro, Maki, Kimura, Ayako, Kinoshita, Yuichi, Miki, Hisanori, Yuri, Takashi, Tsubura, Airo
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320154/
https://ncbi.nlm.nih.gov/pubmed/22481856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.25.27
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