Prostaglandin D(2) Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

Testosterone is necessary for the development of male pattern baldness, known as androgenetic alopecia (AGA); yet, the mechanisms for decreased hair growth in this disorder are unclear. We show that prostaglandin D(2) synthase (PTGDS) is elevated at the mRNA and protein levels in bald scalp compared...

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Main Authors: Garza, Luis A., Liu, Yaping, Yang, Zaixin, Alagesan, Brinda, Lawson, John A., Norberg, Scott M., Loy, Dorothy E., Zhao, Tailun, Blatt, Hanz B., Stanton, David C., Carrasco, Lee, Ahluwalia, Gurpreet, Fischer, Susan M., FitzGerald, Garret A., Cotsarelis, George
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319975/
https://ncbi.nlm.nih.gov/pubmed/22440736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003122
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