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Hypoxia-induced autophagy promotes tumor cell survival and adaptation to anti-angiogenic treatment in glioblastoma

Anti-angiogenic therapy leads to devascularization that limits tumor growth. However, the benefits of angiogenesis inhibitors are typically transient and resistance often develops. In this study, we explored the hypothesis that hypoxia caused by anti-angiogenic therapy induces tumor cell autophagy a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hu, Yu-Long, DeLay, Michael, Jahangiri, Arman, Molinaro, Annette M., Rose, Samuel D., Carbonell, W. Shawn, Aghi, Manish K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319869/
https://ncbi.nlm.nih.gov/pubmed/22447568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3831
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