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The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells

A series of 1-aryl-3-isopropylamino-1-propanone hydrochlorides 1 and a related heterocyclic analog 2 as candidate antineoplastic agents were prepared and the rationale for designing these compounds is presented. A specific objective in this study is the discovery of novel compounds possessing growth...

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Detalhes bibliográficos
Main Authors: Mete, Ebru, Gul, H. Inci, Cetin-Atalay, Rengul, Das, Umashankar, Sahin, Ertan, Gul, Mustafa, Kazaz, Cavit, Dimmock, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319740/
https://ncbi.nlm.nih.gov/pubmed/21319206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ardp.201000194
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