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GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia

Unremitting blood cell production throughout the lifetime of an organism is reliant on hematopoietic stem cells (HSCs). A rare and relatively quiescent cell type harbored in adult bone marrow, HSCs are, on entry into cell cycle fated to self-renew, undergo apoptosis or differentiate to progenitors (...

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Autors principals: Rodrigues, Neil P., Tipping, Alex J., Wang, Zhengke, Enver, Tariq
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319732/
https://ncbi.nlm.nih.gov/pubmed/22192845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2011.12.004
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