Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing

Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the molecular lesion is still laborious and involves time-consuming genetic mapping. Here, we show that high-throughput sequencing of the whole...

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Main Authors: Voz, Marianne L., Coppieters, Wouter, Manfroid, Isabelle, Baudhuin, Ariane, Von Berg, Virginie, Charlier, Carole, Meyer, Dirk, Driever, Wolfgang, Martial, Joseph A., Peers, Bernard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319596/
https://ncbi.nlm.nih.gov/pubmed/22496837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034671
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