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GEP Constitutes a Negative Feedback Loop with MyoD and Acts as a Novel Mediator in Controlling Skeletal Muscle Differentiation

Granulin-epithelin precursor (GEP) is an autocrine growth factor that has been implicated in embryonic development, tissue repair, tumorigenesis, and inflammation. Here we report that GEP was expressed in skeletal muscle tissue and its level was differentially altered in the course of C2C12 myoblast...

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Detalhes bibliográficos
Main Authors: Wang, Dawei, Bai, Xiaohui, Tian, Qingyun, Lai, Yongjie, Lin, Edward A., Shi, Yongxiang, Mu, Xiaodong, Feng, Jian Q., Carlson, Cathy S., Liu, Chuan-ju
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319484/
https://ncbi.nlm.nih.gov/pubmed/22179841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0901-5
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