Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model

Clinical-grade Doxorubicin encapsulated low temperature sensitive liposomes (LTSLs) were combined with a clinical magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) platform to investigate in-vivo image-guided drug delivery. Plasma pharmacokinetics were determined in 3 rabbits. Fi...

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Hlavní autoři: Ranjan, Ashish, Jacobs, Genevieve, Woods, David L., Negussie, Ayele H., Partanen, Ari, Yarmolenko, Pavel S., Gacchina, Carmen E., Sharma, Karun V., Frenkel, Victor, Wood, Bradford J., Dreher, Matthew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319290/
https://ncbi.nlm.nih.gov/pubmed/22210162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.12.011
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