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TOR Signaling Regulates Ribosome and tRNA Synthesis via LAMMER/Clk and GSK-3 Family Kinases
Target of Rapamycin (TOR)-dependent signaling and the control of cell growth is deregulated in many cancers. However, the signaling molecules downstream of TOR that co-ordinately regulate the synthesis of ribosomes and tRNAs are not well defined. Here we show in yeast that conserved kinases of the L...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319249/ https://ncbi.nlm.nih.gov/pubmed/22364741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.018 |
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