Cooperative binding of initiator protein to replication origin conferred by single amino acid substitution.
The replication initiator protein pi of plasmid R6K binds seven 22 bp direct repeats (DR) in the gamma origin. The pi protein also binds to an inverted repeat (IR) in the operator of its own gene, pir, which lies outside the gamma origin sequences. A genetic system was devised to select for pi prote...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1994
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.20.4211 |
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