Anti-mosquito midgut antibodies block development of Plasmodium falciparum and Plasmodium vivax in multiple species of Anopheles mosquitoes and reduce vector fecundity and survivorship

The mosquito midgut plays a central role in the sporogonic development of malaria parasites. We have found that polyclonal sera, produced against mosquito midguts, blocked the passage of Plasmodium falciparum ookinetes across the midgut, leading to a significant reduction of infections in mosquitoes...

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Autors principals: Lal, Altaf A., Patterson, Pamela S., Sacci, John B., Vaughan, Jefferson A., Paul, Chris, Collins, William E., Wirtz, Robert A., Azad, Abdu F.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC33192/
https://ncbi.nlm.nih.gov/pubmed/11309510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091447398
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